NFL Week 4 2025 Score Predictions: Expert Forecasts Winners, Upsets, and Exact Final Scores
October 4, 2025 | As the 2025 NFL season charges into Week 4, fans and bettors alike are bracing for another round of unpredictability. Week 3 delivered its share of shockers — including a 30-0 Atlanta collapse at Carolina and a resurgent Chicago side dominating Dallas 31-14. But what lies ahead this weekend as all 16 teams gear up for another pivotal round?
Veteran analyst and SportsLine contributor Eric Cohen, who is currently boasting a 73% hit rate on straight-up picks this season, has offered exact score predictions for every Week 4 matchup, giving bettors and fans a strategic edge heading into Sunday.
🧠 A Look Back at Week 3: Upsets Galore
Week 3 served as a reality check for several betting favorites:
- Atlanta (-5.5) got blanked 30-0 by Carolina.
- Green Bay (-7.5) lost in a surprising 13-10 upset in Cleveland.
- Dallas (-1.5) couldn’t contain Chicago in a 31-14 home rout.
- Baltimore (-4.5) was outgunned by Detroit in a 38-30 Monday Night Football thriller.
With those results in mind, Week 4 arrives with added suspense — especially for six home underdogs: Tampa Bay, the New York Giants, Atlanta, Las Vegas, Kansas City, and Dallas.
📊 Top Week 4 Prediction: Eagles to Edge Buccaneers
Among the headline matchups this week is the Eagles (-3.5) traveling to face the Buccaneers — both teams unbeaten at 3-0. Despite Tampa Bay’s recent success in the rivalry (six wins in the last seven), Cohen is leaning toward Philadelphia to win and cover.
“Both teams looked shaky last week, but Philly was up against a quality Rams team,” said Cohen. “The line opened at Eagles -3, which feels right. I trust the oddsmakers here — fade them at your own risk.”
Prediction: Eagles 24, Buccaneers 20
Kickoff: Sunday, 1 p.m. ET
Over/Under: 44.5
With Philadelphia’s defense continuing to improve and Tampa Bay battling injuries, Cohen believes the Eagles’ resilience will be the difference-maker in Florida’s sweltering conditions.
🔍 Watch for the Unexpected: Underdog Set to Win Big
While Cohen isn’t revealing all his score predictions publicly, he has singled out one underdog poised to win outright by more than a touchdown — a call that could flip betting lines ahead of Sunday’s slate.
This prediction, and the rest of his exact score forecasts for every game, are available exclusively through SportsLine. Cohen’s historical accuracy, which includes a 190-95 record during the 2024-25 season (69% accuracy), gives weight to his weekly outlooks.
🧪 Key Matchups to Watch in Week 4
Aside from Eagles vs. Buccaneers, several intriguing narratives unfold in Week 4:
Giants vs. Chargers (-6.5)
Jaxson Dart, the highly touted rookie QB, will make his first start for the New York Giants, facing a tough Chargers defense. This game could offer a glimpse into the future of the Giants’ offense — or expose its growing pains.
Cowboys vs. Packers (-7) — Sunday Night Football
All eyes will be on Micah Parsons, returning from injury to lead a Dallas team seeking redemption after a humbling Week 3 loss. Meanwhile, Green Bay hopes to continue its strong defensive showing against an inconsistent Cowboys offense.
Chiefs vs. Jets
Can Kansas City bounce back after a sluggish September? Patrick Mahomes and Travis Kelce will be tested by a surprisingly resilient Jets defense. Cohen warns not to count out the home underdog here.
💰 Why Exact Score Predictions Matter in Sports Betting
Predicting the exact score of an NFL game may seem like a long shot, but with odds often approaching 100-to-1, even small bets can pay off big. Cohen’s historical success has made him a go-to for both casual bettors and serious sharps.
More than just betting advice, exact scores help shape over/under expectations, prop bets, and parlays — giving fans and gamblers a detailed roadmap for the weekend.
🎯 Where to Get Full Predictions
Eric Cohen’s complete Week 4 NFL exact score picks — including that underdog upset and detailed reasoning for each game — are available via SportsLine, where new subscribers can use promo code: CHAMPIONSHIP for a $1 trial month.
Visit SportsLine.com to view Cohen’s full slate of Week 4 predictions and betting insights.
🏈 Final Thoughts: Expect the Unexpected
The NFL remains one of the most volatile sports betting markets in the world, where last week’s kings can become this week’s cautionary tales. As Week 4 kicks off, bettors are advised to proceed with caution — and insight.
If Cohen’s projections hold, expect another weekend of tight finishes, bold upsets, and playoff-shaping outcomes. Whether you’re tracking fantasy points or placing wagers, Week 4 could be a turning point in the 2025 season.
